*AAT_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 

*ABGA_ECOLI.ecard:
# Similarity:
Belongs to peptidase family M40. 

*ACCC_ECOLI.ecard:
# Similarity:
Contains 1 biotin carboxylase domain. 

*ACRR_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*ADHE_ECOLI.ecard:
# Similarity:
In the N-terminal section; belongs to the aldehyde dehydrogenase family. In the C-terminal section; belongs to the iron- containing alcohol dehydrogenase family. 

*ADIY_ECOLI.ecard:
# Name:
HTH-type transcriptional regulator adiY 

*ADIY_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*AER_ECOLI.ecard:
# Specific_Function:
Signal Transducer For Aerotaxis. The Aerotactic Response Is The Accumulation Of Cells Around Air Bubbles. The Nature Of The Sensory Stimulus Detected By This Protein Is The Proton Motive Force Or Cellular Redox State. It Uses A FAD Prosthetic Group As A Redox Sensor To Monitor Oxygen Levels.

*AER_ECOLI.ecard:
# Similarity:
Contains 1 methyl-accepting transducer domain. Contains 1 PAS (PER-ARNT-SIM) dimerization domain. Contains 1 PAS-associated C-terminal (PAC) domain. 

*AGAR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*AGAY_ECOLI.ecard:
# Similarity:
Belongs to the class II fructose-bisphosphate aldolase family. 

*AHPF_ECOLI.ecard:
# Similarity:
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. 

*ALF_ECOLI.ecard:
# Similarity:
Belongs to the class II fructose-bisphosphate aldolase family. 

*ALLR_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*ANSP_ECOLI.ecard:
# Similarity:
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. 

*APHA_ECOLI.ecard:
# Specific_Function:
Dephosphorylates Several Organic Phosphomonoesters And Catalyzes The Transfer Of Low-Energy Phosphate Groups From Phosphomonoesters To Hydroxyl Groups Of Various Organic Compounds. Preferentially Acts On Aryl Phosphoesters. Maximal Activity At Ph 6-6.5 Toward 5'-Amp, And At Ph 5.5-6 Toward 3'-Amp And Pnpp. Might Function As A Broad-Spectrum Dephosphorylating Enzyme Able To Scavenge Both 3'- And 5'-Nucleotides And Also Additional Organic Phosphomonoesters.

*APPY_ECOLI.ecard:
# Name:
HTH-type transcriptional regulator appY 

*APPY_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*ARAC_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*ARGD_ECOLI.ecard:
# Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 

*ARGM_ECOLI.ecard:
# Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 

*ARGR_ECOLI.ecard:
# Specific_Function:
Negatively Controls The Expression Of The Four Operons Of Arginine Biosynthesis In Addition To The Carab Operon. Predominantly Interacts With A/T Residues In Arg Boxes. It Also Binds To A Specific Site In Cer Locus. Thus It Is Essential For Cer-Mediated Site-Specific Recombination In Cole1. It Is Necessary For Monomerization Of The Plasmid Cole1.

*AROP_ECOLI.ecard:
# Similarity:
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. 

*ARSR_ECOLI.ecard:
# Similarity:
Contains 1 HTH arsR-type DNA-binding domain. 

*ARTI_ECOLI.ecard:
# Specific_Function:
Binds Arginine; Part Of The Arginine Periplasmic Transport System.

*ARTJ_ECOLI.ecard:
# Specific_Function:
Binds Arginine; Part Of The Arginine Periplasmic Transport System.

*ASNB_ECOLI.ecard:
# Similarity:
Belongs to the asparagine synthetase family. Contains 1 type-2 glutamine amidotransferase domain. 

*ATP6_ECOLI.ecard:
# Alternate_Names:
ATPase protein 6;

*AVTA_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 

*BCR_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. Bcr/cmlA family. 

*BETI_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*BGLJ_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. 

*BIOA_ECOLI.ecard:
# Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 

*BIOF_ECOLI.ecard:
# Similarity:
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. 

*C562_ECOLI.ecard:
# Specific_Function:
Electron-Transport Protein Of Unknown Function.

*CAIE_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*CDD_ECOLI.ecard:
# Similarity:
Belongs to the cytidine and deoxycytidylate deaminase family. 

*CHEB_ECOLI.ecard:
# Similarity:
Contains 1 cheB-type methylesterase domain. Contains 1 response regulatory domain. 

*CRP_ECOLI.ecard:
# Similarity:
Contains 1 cyclic nucleotide-binding domain. Contains 1 HTH crp/fnr-type DNA-binding domain. 

*CSDA_ECOLI.ecard:
# Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. 

*CSDB_ECOLI.ecard:
# Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. 

*CSGD_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. 

*CSPA_ECOLI.ecard:
# Specific_Function:
Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'.

*CSRA_ECOLI.ecard:
# Specific_Function:
Affects Glycogen Biosynthesis, Gluconeogenesis, Cell Size And Surface Properties. Regulates Glycogen Synthesis Under Both Aerobic And Anaerobic Conditions. Seems To Accelerate The Degradation Of Glg Gene Transcripts, Potentially Through Selective RNA Binding. Acts To Inhibit Interaction Between The Letd Protein And The A Subunit Of DNA Gyrase.

*CYSE_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*CYSJ_ECOLI.ecard:
# Specific_Function:
Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. The Flavo-Protein Component Catalyzes The Electron Flow From Nadph -> FAD -> Fmn To The Hemoprotein Component.

*DACA_ECOLI.ecard:
# Similarity:
Belongs to peptidase family S11. 

*DACC_ECOLI.ecard:
# Similarity:
Belongs to peptidase family S11. 

*DACD_ECOLI.ecard:
# Similarity:
Belongs to peptidase family S11. 

*DAPD_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*DCLZ_ECOLI.ecard:
# Specific_Function:
Ldc Is Constitutively But Weakly Expressed Under Various Conditions.

*DCUD_ECOLI.ecard:
# Specific_Function:
May Have A Role In The Transport Of Dicarboxylates From The Periplasm Across The Inner Membrane. Seems Not To Be Essential For Growth. It Is Likely To Be A Cryptic Gene, As No Or Low Expression Has Been Found Under A Number Of Growth Conditions And When Tested With A Large Number Of Potential Substrates.

*DEGP_ECOLI.ecard:
# Specific_Function:
Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq.

*DEGQ_ECOLI.ecard:
# Specific_Function:
Protease With A Shared Specificity With Degp.

*DEOR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*DFP_ECOLI.ecard:
# Name:
Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein) 

*DFP_ECOLI.ecard:
# Gene_Name:
coabc or dfp or c4463

*DFP_ECOLI.ecard:
# EC_Number:
*   4.1.1.36; 6.3.2.5

*DFP_ECOLI.ecard:
# Alternate_Names:
Phosphopantothenoylcysteine decarboxylase; Phosphopantothenate-- cysteine ligase ;

*DFP_ECOLI.ecard:
# Specific_Function:
Catalyzes Two Steps In The Biosynthesis Of Coenzyme A. In The First Step Cysteine Is Conjugated To 4'-Phosphopantothenate To Form 4-Phosphopantothenoylcysteine, In The Latter Compound Is Decarboxylated To Form 4'-Phosphopantotheine.

*DFP_ECOLI.ecard:
# Similarity:
In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily. 

*DHAL_ECOLI.ecard:
# Specific_Function:
Weak But Measurable Aldh Enzyme Activity That Prefers Nadp Over NAD As Coenzyme.

*DKSA_ECOLI.ecard:
# Specific_Function:
Dosage-Dependent Suppressor Of A Dnak Deletion Mutation. It Suppressed Not Only The Temperature-Sensitive Growth But Also The Filamentous Phenotype Of The Dnak Deletion Strain, While The Defect Of Lambda Growth Is Not Suppressed.

*DLDH_ECOLI.ecard:
# Alternate_Names:
E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; Dihydrolipoamide dehydrogenase; Glycine cleavage system L protein;

*DLDH_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. 

*DMA_ECOLI.ecard:
# Specific_Function:
Methylates DNA Within The Sequence GATC And Protects The DNA From Cleavage By The Restriction Endonuclease Mboi. Although It Shares Sequence Specificity With A Number Of Type II Restriction Endonucleases And Methylases, It Is Thought To Act In Postreplication Mismatch Repair Rather Than As A Part Of A Restriction Modification System. May Also Play A Role In DNA Replication.

*DNAA_ECOLI.ecard:
# Specific_Function:
Plays An Important Role In The Initiation And Regulation Of Chromosomal Replication. Binds To The Origin Of Replication; It Binds Specifically Double-Stranded DNA At A 9 Bp Consensus (Dnaa Box): 5'-TTATC[Ca]A[Ca]A-3'. Dnaa Binds To ATP And To Acidic Phospholipids. Dnaa Can Inhibit Its Own Gene Expression As Well As That Of Other Genes Such As Dam, Rpoh, Ftsa And Mioc.

*DNAJ_ECOLI.ecard:
# Specific_Function:
Interacts With Dnak To Disassemble A Protein Complex At The Phage Lambda Origin Of Replication. Stimulates, Jointly With Grpe, The Atpase Activity Of Dnak.

*DNAJ_ECOLI.ecard:
# Similarity:
Belongs to the dnaJ family. Contains 1 CR domain. Contains 1 J domain. 

*DPPA_ECOLI.ecard:
# Specific_Function:
Dipeptide-Binding Protein Of A Transport System That Can Be Subject To Osmotic Shock. Dppa Is Also Required For Peptide Chemotaxis.

*EGO_ECOLI.ecard:
# Specific_Function:
Probably Part Of A Binding-Protein-Dependent Transport System Ego/Ydeyz. Probably Responsible For Energy Coupling To The Transport System. This Protein Is Essential For Aerobic Growth.

*EMRB_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. EmrB family. 

*EMRD_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*EMRY_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. EmrB family. 

*ENVR_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*ENVY_ECOLI.ecard:
# Specific_Function:
Influences The Temperature-Dependent Expression Of Several E. coli Envelope Proteins, Most Notably The Porins Ompf And Ompc And The Lambda Receptor, Lamb.

*ENVY_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*ENVZ_ECOLI.ecard:
# Specific_Function:
Member Of The Two-Component Regulatory System Envz/Ompr Involved In The Regulation Of Osmoregulation (Genes Ompf And Ompc). Envz Functions As A Membrane-Associated Protein Kinase That Phosphorylates Ompr In Response To Environmental Signals.

*EUTR_ECOLI.ecard:
# Name:
HTH-type transcriptional regulator eutR 

*EUTR_ECOLI.ecard:
# Alternate_Names:
Ethanolamine operon regulatory protein

*EUTR_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*EVGA_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*FEAR_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*FECI_ECOLI.ecard:
# Specific_Function:
Sigma Factors Are Initiation Factors That Promote The Attachment Of RNA Polymerase To Specific Initiation Sites And Are Then Released. This Sigma Factor Regulates The Fec Genes For Iron Dicitrate Transport (Probable).

*FHUB_ECOLI.ecard:
# Specific_Function:
Involved In The High-Affinity Transport Of Iron(III)- Ferrichrome Into The E. coli Cell.

*FHUD_ECOLI.ecard:
# Specific_Function:
Involved In The High-Affinity Transport Of Iron(III)- Ferrichrome Into The Cell. Binds To All Hydroxamate Siderophores.

*FIMB_ECOLI.ecard:
# Specific_Function:
Fimb Is One Of The 2 Regulatory Proteins Which Control The Phase Variation Of Type 1 Fimbriae In E. coli. These Proteins Mediate The Periodic Inversion Of A 300bp DNA Segment That Harbors The Promoter For The Fimbrial Structural Gene, Fima. Fimb Switches Fima On.

*FIME_ECOLI.ecard:
# Specific_Function:
Fime Is One Of The 2 Regulatory Proteins Which Control The Phase Variation Of Type 1 Fimbriae In E. coli. These Proteins Mediate The Periodic Inversion Of A 300bp DNA Segment That Harbors The Promoter For The Fimbrial Structural Gene, Fima. Fime Switches Fima Off.

*FIMF_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*FIMG_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*FIMH_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*FIMI_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*FIMZ_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*FKBX_ECOLI.ecard:
# Specific_Function:
Ppiases Accelerate The Folding Of Proteins. Substrate Specificity Carried Out With Suc-Ala-Xaa-Pro-Phe-4-Nitroanilide, Where Xaa Is The Amino Acid Tested, Was Found To Be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln.

*FLC1_ECOLI.ecard:
# Similarity:
Not Available

*FLIA_ECOLI.ecard:
# Specific_Function:
Sigma Factors Are Initiation Factors That Promote The Attachment Of RNA Polymerase To Specific Initiation Sites And Are Then Released. This Alternative Sigma Factor Is Specific For Class 3 Flagellar Operons.

*FLIH_ECOLI.ecard:
# Similarity:
Belongs to the fliH family. 

*FLIJ_ECOLI.ecard:
# Similarity:
Belongs to the fliJ family. 

*FLIK_ECOLI.ecard:
# Similarity:
Belongs to the fliK family. 

*FLMA_ECOLI.ecard:
# Specific_Function:
When Overexpressed Kills The Cells From The Inside By Interfering With A Vital Function In The Cell Membrane.  Flma Extends The Life Of Unstable Plasmids.

*FM1A_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*FNR_ECOLI.ecard:
# Similarity:
Contains 1 cyclic nucleotide-binding domain. Contains 1 HTH crp/fnr-type DNA-binding domain. 

*FUCR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*GABP_ECOLI.ecard:
# Similarity:
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. 

*GABT_ECOLI.ecard:
# Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 

*GADX_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*GATR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*GATY_ECOLI.ecard:
# Similarity:
Belongs to the class II fructose-bisphosphate aldolase family. 

*GLMU_ECOLI.ecard:
# EC_Number:
*   2.7.7.23; 2.3.1.157

*GLMU_ECOLI.ecard:
# Similarity:
In the C-terminal section; belongs to the transferase hexapeptide repeat family. 

*GLNB_ECOLI.ecard:
# Specific_Function:
P-II Indirectly Controls The Transcription Of The Glutamine Synthetase Gene (Glna). P-II Prevents Nr-II-Catalyzed Conversion Of Nr-I To Nr-I-Phosphate, The Transcriptional Activator Of Glna. When P-II Is Uridylylated To P-II-Ump, These Events Are Reversed. When The Ratio Of Gln To 2-Ketoglutarate Decreases, P-II Is Uridylylated To P-II-Ump, Which Causes The Deadenylylation Of Glutamine Synthetase By Glne, So Activating The Enzyme.

*GLNK_ECOLI.ecard:
# Specific_Function:
P-II Indirectly Controls The Transcription Of The Glutamine Synthetase Gene (Glna). P-II Prevents Nr-II-Catalyzed Conversion Of Nr-I To Nr-I-Phosphate, The Transcriptional Activator Of Glna. When P-II Is Uridylylated To P-II-Ump, These Events Are Reversed. When The Ratio Of Gln To 2-Ketoglutarate Decreases, P-II Is Uridylylated To P-II-Ump, Which Causes The Deadenylylation Of Glutamine Synthetase By Glne, So Activating The Enzyme (By Similarity).

*GLPB_ECOLI.ecard:
# Alternate_Names:
Anaerobic G-3-P dehydrogenase subunit B; Anaerobic G3Pdhase B;

*GLPB_ECOLI.ecard:
# Similarity:
Belongs to the anaerobic G-3-P dehydrogenase subunit B family. 

*GLPR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*GOAG_ECOLI.ecard:
# Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 

*GSA_ECOLI.ecard:
# Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 

*GSHR_ECOLI.ecard:
# Specific_Function:
Maintains High Levels Of Reduced Glutathione In The Cytosol.

*GSHR_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. 

*GSP_ECOLI.ecard:
# Similarity:
Contains 1 CHAP domain. 

*GT_ECOLI.ecard:
# Specific_Function:
Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles.

*GUAA_ECOLI.ecard:
# Alternate_Names:
Glutamine amidotransferase; GMP synthetase; GMPS;

*GUAA_ECOLI.ecard:
# Specific_Function:
Catalyzes The Synthesis Of Gmp From Xmp.

*GUAA_ECOLI.ecard:
# Similarity:
Contains 1 GMP-binding domain. Contains 1 type-1 glutamine amidotransferase domain. 

*GUAC_ECOLI.ecard:
# Gene_Name:
guaC

*GUAC_ECOLI.ecard:
# Similarity:
Belongs to the IMPDH/GMPR family. GuaC subfamily 1. 

*HCAE_ECOLI.ecard:
# Specific_Function:
Part Of The Multicomponent 3-Phenylpropionate Dioxygenase. Converts 3-Phenylpropionic Acid (Pp) Into Cis-3-(3- Carboxyethyl)-3,5-Cyclohexadiene-1,2-Diol (Pp-Dihydrodiol).

*HCAF_ECOLI.ecard:
# Specific_Function:
Part Of The Multicomponent 3-Phenylpropionate Dioxygenase. Converts 3-Phenylpropionic Acid (Pp) Into Cis-3-(3- Carboxyethyl)-3,5-Cyclohexadiene-1,2-Diol (Pp-Dihydrodiol).

*HEXR_ECOLI.ecard:
# Specific_Function:
Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity).

*HEXR_ECOLI.ecard:
# Similarity:
Contains 1 HTH rpiR-type DNA-binding domain. Contains 1 SIS domain. 

*HIPB_ECOLI.ecard:
# Specific_Function:
Binds To Operator Sites With The Consensus Sequence 5-'Tatccn(8)GGATA-3' And Repress The Hip Operon Promoter.

*HIS8_ECOLI.ecard:
# Similarity:
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. 

*HISJ_ECOLI.ecard:
# Specific_Function:
Component Of The High-Affinity Histidine Permease, A Binding-Protein-Dependent Transport System. The Other Components Are Proteins Hisq, Hism, And Hisp.

*HPRT_ECOLI.ecard:
# Specific_Function:
This Enzyme Acts Exclusively On Hypoxanthine; It Does Not Act On Guanine (By Similarity).

*HSLR_ECOLI.ecard:
# Similarity:
Belongs to the HSP15 family. Contains 1 S4 RNA-binding domain. 

*IADA_ECOLI.ecard:
# Similarity:
Belongs to peptidase family M38. 

*ICLR_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*IDND_ECOLI.ecard:
# Specific_Function:
Catalyzes The NADH/Nadph-Dependent Oxidation Of L- Idonate To 5-Ketogluconate (5kg).

*ILVE_ECOLI.ecard:
# Similarity:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. 

*ILVM_ECOLI.ecard:
# Similarity:
Not Available

*INTD_ECOLI.ecard:
# Similarity:
Belongs to the "phage" integrase family. 

*INTE_ECOLI.ecard:
# Similarity:
Belongs to the "phage" integrase family. 

*ISCS_ECOLI.ecard:
# Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/iscS subfamily. 

*KBL_ECOLI.ecard:
# Similarity:
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. 

*KDGR_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*KEFB_ECOLI.ecard:
# Similarity:
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily. 

*KEFC_ECOLI.ecard:
# Similarity:
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily. 

*LIVF_ECOLI.ecard:
# Similarity:
Belongs to the ABC transporter family. 

*LIVG_ECOLI.ecard:
# Similarity:
Belongs to the ABC transporter family. 

*LNT_ECOLI.ecard:
# Similarity:
Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. Contains 1 CN hydrolase domain. 

*LYSP_ECOLI.ecard:
# Similarity:
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. 

*MAA_ECOLI.ecard:
# Specific_Function:
Acetylates Maltose And Other Sugars.

*MAA_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*MALT_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. 

*MALY_ECOLI.ecard:
# Similarity:
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/patB subfamily. 

*MANA_ECOLI.ecard:
# Specific_Function:
Involved In The Conversion Of Glucose To Gdp-L-Fucose, Which Can Be Converted To L-Fucose, A Capsular Polysaccharide.

*MARA_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*MARR_ECOLI.ecard:
# Similarity:
Contains 1 HTH marR-type DNA-binding domain. 

*MCP1_ECOLI.ecard:
# Specific_Function:
Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids.  Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Transduce A Signal From The Outside To The Inside Of The Cell, And Facilitate Sensory Adaptation Through The Variation Of The Level Of Methylation. Attractants Increase The Level Of Methylation While Repellents Decrease The Level Of Methylation, The Methyl Groups Are Added By The Methyltransferase Cher And Removed By The Methylesterase Cheb.

*MCP1_ECOLI.ecard:
# Similarity:
Contains 1 HAMP domain. Contains 1 methyl-accepting transducer domain. 

*MCP2_ECOLI.ecard:
# Similarity:
Contains 1 HAMP domain. Contains 1 methyl-accepting transducer domain. 

*MCP3_ECOLI.ecard:
# Similarity:
Contains 1 HAMP domain. Contains 1 methyl-accepting transducer domain. 

*MCP4_ECOLI.ecard:
# Similarity:
Contains 1 HAMP domain. Contains 1 methyl-accepting transducer domain. 

*MDFA_ECOLI.ecard:
# Specific_Function:
Efflux Pump Driven By The Proton Motive Force. Confers Resistance To Basic, Aromatic And Lipophilic Drugs As Well As Neutral, Non-Aromatic, Zwitterionic Or Nonaromatic Hydrophilic Antibiotics.

*MDFA_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*MELB_ECOLI.ecard:
# Specific_Function:
Responsible For Melibiose Transport. It Is Capable Of Using Hydrogen, Sodium, And Lithium Cations As Coupling Cations For Cotransport, Depending On The Particular Sugar Transported (Symport System).

*MELR_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*MENB_ECOLI.ecard:
# Specific_Function:
Converts O-Succinylbenzoyl-CoA (Osb-CoA) To 1,4- Dihydroxy-2-Naphthoic Acid (Dhna).

*MHPB_ECOLI.ecard:
# Similarity:
Not Available

*MHPR_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*MOEB_ECOLI.ecard:
# Specific_Function:
Involved In The Biosynthesis Of A Demolybdo Cofactor (Molybdopterin), Necessary For Molybdoenzymes. Plays A Role In The Activation Of The Small Subunit Of The Molybdopterin Converting Factor (Moad).

*MPRA_ECOLI.ecard:
# Similarity:
Contains 1 HTH marR-type DNA-binding domain. 

*MUKB_ECOLI.ecard:
# Specific_Function:
Plays A Central Role In Chromosome Condensation, Segregation And Cell Cycle Progression. Functions As A Homodimer, Which Is Essential For Chromosome Partition. Involved In Negative DNA Supercoiling In Vivo, And By This Means Organize And Compact Chromosomes. May Achieve Or Facilitate Chromosome Segregation By Condensation DNA From Both Sides Of A Centrally Located Replisome During Cell Division.

*MUKB_ECOLI.ecard:
# Other_Databases:
- ECOCYC: EG10618
- EcoGene: EG10618
- EMBL: X57550
- Pfam: PF04310
- PIR: C64832

*MUTL_ECOLI.ecard:
# Specific_Function:
This Protein Is Involved In The Repair Of Mismatches In DNA. It Is Required For Dam-Dependent Methyl-Directed DNA Mismatch Repair. May Act As A "Molecular Matchmaker", A Protein That Promotes The Formation Of A Stable Complex Between Two Or More DNA-Binding Proteins In An ATP-Dependent Manner Without Itself Being Part Of The Final Effector Complex. The Atpase Activity Of Mutl Is Stimulated By DNA.

*NARH_ECOLI.ecard:
# Similarity:
Not Available

*NARI_ECOLI.ecard:
# Similarity:
Not Available

*NARJ_ECOLI.ecard:
# Similarity:
Not Available

*NARL_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*NARP_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*NARW_ECOLI.ecard:
# Similarity:
Not Available

*NARY_ECOLI.ecard:
# Similarity:
Not Available

*NHAB_ECOLI.ecard:
# Specific_Function:
Na(+)/H(+) Antiporter. Has A High Affinity For Na(+) And A Relative Independence Of Its Activity On Ph.

*NRDH_ECOLI.ecard:
# Specific_Function:
Electron Transport System For The Ribonucleotide Reductase System Nrdef.

*NUSA_ECOLI.ecard:
# Specific_Function:
Participates In Both The Termination And Antitermination Of Transcription. Nusa Binds Directly To The Core Enzyme Of The DNA-Dependent RNA Polymerase. Nusa Also Interacts With Lambda N Protein, RNA, Rho Factor, And Perhaps Nusb. Binds RNA.

*NUSA_ECOLI.ecard:
# Similarity:
Belongs to the nusA family. Contains 1 KH domain. Contains 1 S1 motif domain. 

*NUSB_ECOLI.ecard:
# Specific_Function:
One Of The Proteins Essential For The Formation Of The RNA Polymerase Antitermination Complex In The Presence Of Lambda Phage N Protein. However, It Is Involved In The Transcription Termination Process At Certain Sites During Normal Bacterial Growth. Binds To The Boxa RNA Motif.

*OAT_ECOLI.ecard:
# Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 

*ODO2_ECOLI.ecard:
# Name:
Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex  

*ODO2_ECOLI.ecard:
# Alternate_Names:
E2; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex;

*ODP2_ECOLI.ecard:
# Name:
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex  

*ODP2_ECOLI.ecard:
# Alternate_Names:
E2; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex;

*PA1_ECOLI.ecard:
# Specific_Function:
Hydrolysis Of Phosphatidylcholine With Phospholipase A2 (Ec 3.1.1.4) And Phospholipase A1 (Ec 3.1.1.32) Activities. Required For Efficient Secretion Of Bacteriocins; Seems To Be Dormant In Normal Growing Cells.

*PAAY_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*PABC_ECOLI.ecard:
# Similarity:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. 

*PBP4_ECOLI.ecard:
# Similarity:
Belongs to peptidase family S13. 

*PBP7_ECOLI.ecard:
# Similarity:
Belongs to peptidase family S11. 

*PDXH_ECOLI.ecard:
# Specific_Function:
Oxidizes Pnp And Pmp Into Pyridoxal 5'-Phosphate (Plp).

*PEPT_ECOLI.ecard:
# Specific_Function:
Releases The N-Terminal Amino Acid From Tripeptides. Has A Preference For Tripeptides Containing A N-Terminal Methionine Or Leucine (By Similarity).

*PERM_ECOLI.ecard:
# Similarity:
Belongs to the UPF0118 (perM) family. 

*PHEP_ECOLI.ecard:
# Similarity:
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. 

*PHNH_ECOLI.ecard:
# Similarity:
Not Available

*PHOE_ECOLI.ecard:
# Specific_Function:
Uptake Of Inorganic Phosphate, Phosphorylated Compounds, And Some Other Negatively Charged Solutes.

*PHOL_ECOLI.ecard:
# Similarity:
Belongs to the phoH family. 

*PHSC_ECOLI.ecard:
# Similarity:
Not Available

*PIL1_ECOLI.ecard:
# Similarity:
Belongs to the traA family. 

*PLSC_ECOLI.ecard:
# Specific_Function:
Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor.

*POTD_ECOLI.ecard:
# Similarity:
Belongs to the bacterial extracellular solute-binding protein potD/potF family. 

*POTF_ECOLI.ecard:
# Similarity:
Belongs to the bacterial extracellular solute-binding protein potD/potF family. 

*PPB_ECOLI.ecard:
# Other_Databases:
- ECOCYC: EG10727
- EcoGene: EG10727
- EMBL: X04586
- InterPro: IPR001952
- Pfam: PF00245
- PIR: A00776
- PRINTS: PR00113
- PROSITE: PS00123

*PPDD_ECOLI.ecard:
# Similarity:
Belongs to the N-Me-Phe pili family. 

*PPX_ECOLI.ecard:
# Specific_Function:
Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate.

*PQQL_ECOLI.ecard:
# Similarity:
Belongs to peptidase family M16. 

*PRIC_ECOLI.ecard:
# Specific_Function:
Pria Recognizes A Specific Hairpin Sequence On Bacteriophage Phi X174 Ssdna. This Structure Is Then Recognized And Bound By Proteins Prib And Pric. Formation Of The Primosome Proceeds With The Subsequent Actions Of Dnab, Dnac, Dnat And Primase.

*PROY_ECOLI.ecard:
# Similarity:
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. 

*PSPB_ECOLI.ecard:
# Specific_Function:
The Phage Shock Protein (Psp) Operon (Pspabce) May Play A Significant Role In The Competition For Survival Under Nutrient- Or Energy-Limited Conditions. Pspb Is Involved In Transcription Regulation.

*PSPC_ECOLI.ecard:
# Specific_Function:
The Phage Shock Protein (Psp) Operon (Pspabce) May Play A Significant Role In The Competition For Survival Under Nutrient- Or Energy-Limited Conditions. Pspc Is Involved In Transcription Regulation.

*PSTS_ECOLI.ecard:
# Specific_Function:
Required For Binding-Protein-Mediated Phosphate Transport.

*PT1P_ECOLI.ecard:
# Specific_Function:
Could Function In The Transcriptional Regulation Of Sigma-54 Dependent Operons In Conjunction With The Npr (Ptso) And Iiantr (Ptsn) Proteins Thereby Providing A Link Between Carbon And Nitrogen Assimilatory Pathways.

*PTFA_ECOLI.ecard:
# Similarity:
Contains 1 Hpr domain. Contains 1 PTS EIIA domain. 

*PTGB_ECOLI.ecard:
# Specific_Function:
Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active Transport System. The Iicd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The Iia Domain Contains The Primary Phosphorylation Site (The Donor Is Phospho-Hpr); Iia Transfers Its Phosphoryl Group To The Iib Domain Which Finally Transfers It To The Sugar. This Enzyme Is Also A Chemoreceptor Monitoring The Environment For Changes In Sugar Concentration.

*PTSO_ECOLI.ecard:
# Specific_Function:
Seems To Have A Role In Linking Carbon And Nitrogen Assimilation. Probably Acts In A Regulatory Capacity And Could Control The State Of Phosphorylation Of Iia-Ntr (Ptsn).

*PTTB_ECOLI.ecard:
# Specific_Function:
Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active Transport System. Belongs To The Eiibc Domain Type And Lacks A Covalently Bound Eiia Domain. The Iib Domain Contains The Phosphoryl Transfer Domain; The Iic Domain Contains The Transmembrane Channel. The Eii-Tre-Mediated Phosphorylation Of Trehalose Requires The Activity Of Enzyme Iia-Glc, A Component Of The Major Glucose Transport System.

*PTVB_ECOLI.ecard:
# Similarity:
Contains 1 PTS EIIB domain. Contains 1 PTS EIIC domain. 

*RBFA_ECOLI.ecard:
# Specific_Function:
Essential For Efficient Processing Of 16s Rrna. Probably Part Of The 30s Subunit Prior To Or During The Final Step In The Processing Of 16s Free 30s Ribosomal Subunits. Could Be Some Accessory Protein Needed For Efficient Assembly Of The 30s Subunit. May Interact With The 5'Terminal Helix Region Of 16s Rrna. Has Affinity For Free Ribosomal 30s Subunits But Not For 70s Ribosomes.

*RCSA_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. 

*RCSB_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*REDF_ECOLI.ecard:
# Similarity:
Belongs to the "phage" integrase family. 

*RFAK_ECOLI.ecard:
# Similarity:
Not Available

*RFC_ECOLI.ecard:
# Similarity:
Not Available

*RFH_ECOLI.ecard:
# Specific_Function:
Could Be Involved In Translational Termination.

*RHAR_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*RHAS_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*RL10_ECOLI.ecard:
# Specific_Function:
Protein L10 Is Also A Translational Repressor Protein. It Controls The Translation Of The Rpljl-Rpobc Operon By Binding To Its Mrna.

*RL11_ECOLI.ecard:
# Specific_Function:
This Protein Binds Directly To 23s Ribosomal RNA. Forms The L11 Stalk, Which Is Thought To Be Quite Mobile During Translation.

*RL13_ECOLI.ecard:
# Specific_Function:
This Protein Is One Of The Early Assembly Proteins Of The 50s Ribosomal Subunit, Although It Is Not Seen To Bind Rrna By Itself. It Is Important During The Early Stages Of 50s Assembly.

*RL14_ECOLI.ecard:
# Specific_Function:
This Protein Binds Directly To 23s Ribosomal RNA. In The E. coli 70s Ribosome It Has Been Modeled To Make Two Contacts With The 16s Rrna Of The 30s Subunit, Forming Part Of Bridges B5 And B8, Connecting The 2 Subunits. Although The Protein Undergoes Significant Rotation During The Transition From An Initiation To And Ef-G Bound State, The Bridges Remain Stable.

*RL15_ECOLI.ecard:
# Specific_Function:
This Protein Binds The 5s Rrna. It Is Required For The Late Stages Of Subunit Assembly.

*RL16_ECOLI.ecard:
# Specific_Function:
This Protein Binds Directly To 23s Ribosomal RNA And Is Located At The A Site Of The Peptidyltransferase Center. It Has An Essential Role In Subunit Assembly, Which Is Not Well Understood.

*RL18_ECOLI.ecard:
# Specific_Function:
This Is One Of 3 Proteins That Mediate The Attachment Of The 5s Rrna Onto The Large Ribosomal Subunit.

*RL19_ECOLI.ecard:
# Specific_Function:
This Protein Is Located At The 30s-50s Ribosomal Subunit Interface. In The E. coli 70s Ribosome It Has Been Modeled To Make Two Contacts With The 16s Rrna Of The 30s Subunit Forming Part Of Bridges B6 And B8.

*RL1_ECOLI.ecard:
# Specific_Function:
One Of The Primary Rrna Binding Proteins, It Binds Very Close To The 3' End Of The 23s Rrna. Forms Part Of The L1 Stalk. It Is Often Not Seen In Crystal Structures; This And Other Data Suggest This Part Of The Ribosome Is Quite Mobile. This Protein Is Located In The Neighborhood Of The Site Where Elongation Factor Tu Is Bound To The Ribosome.  Protein L1 Is Also A Translational Repressor Protein, It Controls The Translation Of The L11 Operon By Binding To Its Mrna.

*RL20_ECOLI.ecard:
# Specific_Function:
One Of The Primary Rrna Binding Proteins, It Binds Close To The 5' End Of The 23s Rrna. It Is Important During The Early Stages Of 50s Assembly.

*RL21_ECOLI.ecard:
# Specific_Function:
This Protein Binds To 23s Rrna In The Presence Of Protein L20.

*RL22_ECOLI.ecard:
# Specific_Function:
This Protein Binds Specifically To 23s Rrna; Its Binding Is Stimulated By Other Ribosomal Proteins, E.G., L4, L17, And L20. It Is Important During The Early Stages Of 50s Assembly.  The Globular Domain Of The Protein Is One Of The Proteins That Surrounds The Polypeptide Exit Tunnel On The Outside Of The Subunit While An Extended Beta-Hairpin Is Found That Penetrates Into The Center Of The 70s Ribosome.

*RL23_ECOLI.ecard:
# Specific_Function:
Binds To A Specific Region On The 23s Rrna.  One Of The Proteins That Surrounds The Polypeptide Exit Tunnel On The Outside Of The Subunit.

*RL25_ECOLI.ecard:
# Specific_Function:
This Is One Of 3 Proteins That Mediate The Attachment Of The 5s Rrna Onto The Large Ribosomal Subunit.

*RL29_ECOLI.ecard:
# Specific_Function:
One Of The Proteins That Surrounds The Polypeptide Exit Tunnel On The Outside Of The Subunit.

*RL4_ECOLI.ecard:
# Specific_Function:
One Of The Primary Rrna Binding Proteins, This Protein Binds Near The 5' End Of The 23s Rrna. It Is Important During The Early Stages Of 50s Assembly.  Protein L4 Is Also A Translational Repressor Protein. It Controls The Translation Of The S10 Operon (To Which L4 Belongs) By Binding To Its Mrna.

*RL5_ECOLI.ecard:
# Specific_Function:
This Is One Of 3 Proteins That Mediate The Attachment Of The 5s Rrna Onto The Large Ribosomal Subunit. Its Binding Is Enhanced By The Presence Of One Of Proteins L18 Or L25.  In The E. coli 70s Ribosome In The Initiation State It Has Been Modeled To Contact Protein S13 Of The 30s Subunit (Bridge B1b), Connecting The 2 Subunits; The Protein-Protein Contacts Between S13 And L5 In B1b Change In The Model With Bound Ef-G. This Protein Probably Moves During Translation.

*RL9_ECOLI.ecard:
# Specific_Function:
One Of The Primary Rrna Binding Proteins, It Binds Very Close To The 3' End Of The 23s Rrna.

*RNG_ECOLI.ecard:
# Specific_Function:
Involved In The Processing Of The 5'End Of 16s Rrna. Could Be Involved In Chromosome Segregation And Cell Division. It May Be One Of The Components Of The Cytoplasmic Axial Filaments Bundles Or Merely Regulate The Formation Of This Structure.

*RNH_ECOLI.ecard:
# Specific_Function:
Endonuclease That Specifically Degrades The RNA Of RNA- DNA Hybrids. In E. coli Rnase H Participates In DNA Replication; It Helps To Specify The Origin Of Genomic Replication By Suppressing Initiation At Origins Other Than The Oric Locus; Along With The 5'-3' Exonuclease Of Pol1, It Removes RNA Primers From The Okazaki Fragments Of Lagging Strand Synthesis; And It Defines The Origin Of Replication For Cole1-Type Plasmids By Specific Cleavage Of An RNA Preprimer.

*ROB_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*RODA_ECOLI.ecard:
# Specific_Function:
This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation.

*RP32_ECOLI.ecard:
# Specific_Function:
Sigma Factors Are Initiation Factors That Promote The Attachment Of RNA Polymerase To Specific Initiation Sites And Are Then Released. This Sigma Factor Is Responsible For The Expression Of Heat Shock Promoters.

*RP54_ECOLI.ecard:
# Specific_Function:
Sigma Factors Are Initiation Factors That Promote The Attachment Of RNA Polymerase To Specific Initiation Sites And Are Then Released. This Sigma Factor Is Responsible For The Expression Of Enzymes Involved In Arginine Catabolism. The Open Complex (Sigma-54 And Core RNA Polymerase) Serves As The Receptor For The Receipt Of The Melting Signal From The Remotely Bound Activator Protein Glng(Ntrc).

*RPIR_ECOLI.ecard:
# Similarity:
Contains 1 HTH rpiR-type DNA-binding domain. Contains 1 SIS domain. 

*RPOE_ECOLI.ecard:
# Specific_Function:
Sigma Factors Are Initiation Factors That Promote The Attachment Of RNA Polymerase To Specific Initiation Sites And Are Then Released. This Sigma Factor Is Involved In Heat Shock And Oxidative Stress Response; It Is Believed To Control Protein Processing In The Extracytoplasmic Compartment.

*RPSD_ECOLI.ecard:
# Specific_Function:
Sigma Factors Are Initiation Factors That Promote The Attachment Of RNA Polymerase To Specific Initiation Sites And Are Then Released. This Is The Primary Sigma Factor Of This Bacterium.

*RRMA_ECOLI.ecard:
# Similarity:
Not Available

*RS13_ECOLI.ecard:
# Specific_Function:
Located At The Top Of The Head Of The 30s Subunit, It Contacts Several Helices Of The 16s Rrna. In The E. coli 70s Ribosome In The Initiation State It Has Been Modeled To Contact The 23s Rrna (Bridge B1a) And Protein L5 Of The 50s Subunit (Bridge B1b), Connecting The 2 Subunits; Bridge B1a Is Broken In The Model With Bound Ef-G, While The Protein-Protein Contacts Between S13 And L5 In B1b Change. Contacts The Trnas In The A And P Sites (By Similarity).

*RS15_ECOLI.ecard:
# Specific_Function:
In The E. coli 70s Ribosome It Has Been Modeled To Contact The 23s Rrna Of The 50s Subunit Forming Part Of Bridge B4.  This Protein Is One Of The 16s Ribosomal RNA Binding Proteins. Functions At Early Steps In Ribosome Assembly.

*RS17_ECOLI.ecard:
# Specific_Function:
Binds Specifically To The 5' End Of 16s Ribosomal RNA. S17 Is Thought To Be Involved In The Recognition Of Termination Codons.

*RS19_ECOLI.ecard:
# Specific_Function:
In The E. coli 70s Ribosome In The Initiation State It Has Been Modeled To Contact The 23s Rrna Of The 50s Subunit Forming Part Of Bridge B1a; This Bridge Is Broken In The Model With Bound Ef-G.  Protein S19 Forms A Complex With S13 That Binds Strongly To The 16s Ribosomal RNA.

*RS5_ECOLI.ecard:
# Similarity:
Belongs to the S5P family of ribosomal proteins. Contains 1 S5 DRBM domain. 

*RS7_ECOLI.ecard:
# Specific_Function:
One Of The Primary Rrna Binding Proteins, It Binds Directly To 16s Rrna Where It Nucleates Assembly Of The Head Domain Of The 30s Subunit. Is Located At The Subunit Interface Close To The Decoding Center, Where It Has Been Shown To Contact Mrna. Probably Blocks Exit Of The E Site Trna (By Similarity).  Protein S7 Is Also A Translational Repressor Protein; It Regulates The Expression Of The Str Operon Members To Different Degrees By Binding To Its Mrna.

*RSD_ECOLI.ecard:
# Similarity:
Belongs to the rsd/algQ family. 

*RSEA_ECOLI.ecard:
# Similarity:
Belongs to the rseA family. 

*RSEB_ECOLI.ecard:
# Similarity:
Belongs to the rseB family. 

*RSEC_ECOLI.ecard:
# Similarity:
Belongs to the rseC family. 

*RUS_ECOLI.ecard:
# Specific_Function:
Endonuclease That Resolves Holliday Junction Intermediates In Genetic Recombination. Cleaves X-Junctions By Introducing Symmetrical Nicks In Two Strands Of The Same Polarity. Processes Holliday Intermediates Made By Reca. Corrects The Defects In Genetic Recombination And DNA Repair Associated With Inactivation Of Ruvab Or Ruvc.

*RUVA_ECOLI.ecard:
# Specific_Function:
The Ruva-Ruvb Complex In The Presence Of ATP Renatures Cruciform Structure In Supercoiled DNA With Palindromic Sequence, Indicating That It May Promote Strand Exchange Reactions In Homologous Recombination. Ruvab Is An Helicase That Mediates The Holliday Junction Migration By Localized Denaturation And Reannealing. Ruva Stimulates, In The Presence Of DNA, The Weak Atpase Activity Of Ruvb. Binds Both Single- And Double-Stranded DNA (Dsdna). Binds Preferentially To Supercoiled Rather Than To Relaxed Dsdna.

*RUVB_ECOLI.ecard:
# Specific_Function:
The Ruva-Ruvb Complex In The Presence Of ATP Renatures Cruciform Structure In Supercoiled DNA With Palindromic Sequence, Indicating That It May Promote Strand Exchange Reactions In Homologous Recombination. Ruvab Is An Helicase That Mediates The Holliday Junction Migration By Localized Denaturation And Reannealing.

*RZPD_ECOLI.ecard:
# Similarity:
Belongs to peptidase family U8. 

*RZPR_ECOLI.ecard:
# Similarity:
Belongs to peptidase family U8. 

*SANA_ECOLI.ecard:
# Similarity:
Not Available

*SDIA_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. 

*SEQA_ECOLI.ecard:
# Specific_Function:
Negative Regulator Of Replication Initiation. Required For Sequestration, A Process That Blocks Secondary Initiation Events. Could Block The Allosteric Transition Of Dnaa From An Inactive Form To An Active Form. Binds Hemimethylated Oric. This Process Has Been Implicated In The Prevention Of Premature Reinitiation At Newly Replicated Chromosomal Origins.

*SERC_ECOLI.ecard:
# Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. 

*SFMA_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*SFMF_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*SFMH_ECOLI.ecard:
# Similarity:
Not Available

*SFSB_ECOLI.ecard:
# Similarity:
Belongs to the ner transcriptional regulatory family. 

*SGCR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*SOXS_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*SPEA_ECOLI.ecard:
# Specific_Function:
Catalyzes The Biosynthesis Of Agmatine From Arginine (By Similarity).

*SPEA_ECOLI.ecard:
# Similarity:
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. 

*SPEE_ECOLI.ecard:
# Specific_Function:
Spermidine biosynthesis from arginine; third (last) step. 

*SRLR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*SRNB_ECOLI.ecard:
# Specific_Function:
When Overexpressed, Kills The Cells From The Inside By Interfering With A Vital Function In The Cell Membrane. Its Normal Function Is Believed To Be Effective Plasmid Stabilization Through Postsegregational Killing Of Cells That Have Lost F.  Promotes Degradation Of Stable RNA In E. coli.

*SSPA_ECOLI.ecard:
# Specific_Function:
Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It Is Involved In The Transition From P1 Early To P1 Late Gene Expression. Rnk And Sspa Can Functionally Replace P.Aeruginosa Alginate Regulatory Gene Algr2.

*STHA_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. 

*SULA_ECOLI.ecard:
# Specific_Function:
Sula Is A Component Of The Sos System And An Inhibitor Of Cell Division. Accumulation Of Sula Causes Rapid Cessation Of Cell Division And The Appearance Of Long, Non-Septate Filaments. The Expression Of Sula Is Repressed By The Lexa Protein. Ftsz Seems To Be The Target Of Sula.

*T1MK_ECOLI.ecard:
# Specific_Function:
The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To The Same Target Sequence But Cutting The DNA Some Distance From This Site. Whether The DNA Is Cut Or Modified Depends On The Methylation State Of The Target Sequence. When The Target Site Is Unmodified, The DNA Is Cut. When The Target Site Is Hemimethylated, The Complex Acts As A Maintenance Mtase Modifying The DNA So That Both Strands Become Methylated. The Ecoki Enzyme Recognizes 5'-Aacn(6)GTGC-3'.

*T1RK_ECOLI.ecard:
# Specific_Function:
The Ecoki Enzyme Recognizes 5'-Aacn(6)GTGC-3'. Subunit R Is Required For Both Nuclease And Atpase Activities, But Not For Modification.

*T1SK_ECOLI.ecard:
# Specific_Function:
The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To The Same Target Sequence But Cutting The DNA Some Distance From This Site. Whether The DNA Is Cut Or Modified Depends On The Methylation State Of The Target Sequence. When The Target Site Is Unmodified, The DNA Is Cut. When The Target Site Is Hemimethylated, The Complex Acts As A Maintenance Mtase Modifying The DNA So That Both Strands Become Methylated. Subunit S Dictates DNA Sequences Specificity. The Ecoki Enzyme Recognizes 5'- Aacn(6)GTGC-3'.

*TAUD_ECOLI.ecard:
# Similarity:
Belongs to the tfdA dioxygenase family. 

*THGA_ECOLI.ecard:
# Alternate_Names:
GAT; Thiogalactoside acetyltransferase;

*THGA_ECOLI.ecard:
# Specific_Function:
May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell.

*THGA_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*TKRA_ECOLI.ecard:
# Specific_Function:
Catalyzes The Nadph-Dependent Reduction Of 2,5-Diketo-D- Gluconate (25dkg) To 5-Keto-D-Gluconate (5kdg), 2-Keto-D-Gluconate (2kdg) To D-Gluconate, And 2-Keto-L-Gulonate (2klg) To L-Idonate (Ia).

*TNAB_ECOLI.ecard:
# Specific_Function:
Involved In Tryptophan Transport Across The Cytoplasmic Membrane. Plays A Role In Transporting Tryptophan Which Is To Be Used Catabolically.

*TONB_ECOLI.ecard:
# Specific_Function:
Interacts With Outer Membrane Receptor Proteins That Carry Out High-Affinity Binding And Energy Dependent Uptake Into The Periplasmic Space Of Specific Substrates Such As Cobalamin, And Various Iron Compounds (Such As Iron Dicitrate, Enterochelin, Aerobactin, Etc.). In The Absence Of Tonb These Receptors Bind Their Substrates But Do Not Carry Out Active Transport. Tonb Also Interacts With Some Colicins And Is Involved In The Energy- Dependent, Irreversible Steps Of Bacteriophages Phi 80 And T1 Infection. It Could Act To Transduce Energy From The Cytoplasmic Membrane To Specific Energy-Requiring Processes In The Outer Membrane, Resulting In The Release Into The Periplasm Of Ligands Bound By These Outer Membrane Proteins.

*TRB1_ECOLI.ecard:
# Similarity:
Belongs to the traB family. 

*TRE1_ECOLI.ecard:
# Similarity:
Belongs to the traE family. 

*TRI1_ECOLI.ecard:
# Similarity:
Strong, to traI of plasmid IncFII R100. 

*TRL1_ECOLI.ecard:
# Similarity:
Not Available

*TRPG_ECOLI.ecard:
# Similarity:
In the C-terminal section; belongs to the anthranilate phosphoribosyltransferase family. Contains 1 type-1 glutamine amidotransferase domain. 

*TRX1_ECOLI.ecard:
# Similarity:
Belongs to the traX family. 

*TRXB_ECOLI.ecard:
# Similarity:
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. 

*TRY1_ECOLI.ecard:
# Similarity:
Belongs to the traY family. 

*TTK_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*TYRB_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 

*UGPB_ECOLI.ecard:
# Specific_Function:
Sn-Glycerol-3-Phosphate And Glycerophosphoryl Diester- Binding Protein Interacts With The Binding Protein-Dependent Transport System Ugpace.

*UHPA_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*UIDR_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*UVRD_ECOLI.ecard:
# Specific_Function:
Has Both Atpase And Helicase Activities. Unwinds DNA Duplexes With 3' To 5' Polarity With Respect To The Bound Strand And Initiates Unwinding Most Effectively When A Single-Stranded Region Is Present. Involved In The Post-Incision Events Of Nucleotide Excision Repair And Methyl-Directed Mismatch Repair.

*UVRY_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*VSR_ECOLI.ecard:
# Specific_Function:
Deamination Of 5-Methylcytosine In DNA Results In T/G Mismatches. If Unrepaired, These Mismatches Can Lead To C-To-C Transition Mutations. The Very Short Patch (Vsp) Repair Process In E. coli Counteracts The Mutagenic Process By Repairing The Mismatches In Favor Of The G-Containing Strand. This Enzyme Is An Endonuclease That Nicks Double-Stranded DNA Within The Sequence Ct(At)Gn Or Nt(At)Gg Next To The Thymidine Residue That Is Mismatched To 2'-Deoxyguanosine. The Incision Is Mismatch- Dependent And Strand-Specific.

*WBBJ_ECOLI.ecard:
# Specific_Function:
Putative O-Acetyltransferase That Transfers An O-Acetyl Group To The O Antigen.

*WBBJ_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*WCAB_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*WCAF_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*WCAK_ECOLI.ecard:
# EC_Number:
*  2.-.-.-

*WCAK_ECOLI.ecard:
# Similarity:
Belongs to the polysaccharide pyruvyl transferase family. 

*XAPA_ECOLI.ecard:
# Specific_Function:
The Nucleoside Phosphorylases Catalyze The Phosphorolytic Breakdown Of The N-Glycosidic Bond In The Nucleoside Molecule, With The Formation Of The Corresponding Free Bases And Pentose-1-Phosphate. This Protein Can Degrade All Purine Nucleosides Except Adenosine And Deoxyadenosine.

*XYLR_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YADC_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YADG_ECOLI.ecard:
# Similarity:
Belongs to the ABC transporter family. 

*YADN_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YAEB_ECOLI.ecard:
# Similarity:
Belongs to the UPF0066 (virR) family. 

*YAFY_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yafY 

*YAFY_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*YAGH_ECOLI.ecard:
# Similarity:
Belongs to family 43 of glycosyl hydrolases. 

*YAGI_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yagI 

*YAGI_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*YAGX_ECOLI.ecard:
# Similarity:
Some, to E.coli plasmid NTP513 CFA fimbria subunit C (cfaC). 

*YAJC_ECOLI.ecard:
# Similarity:
Belongs to the UPF0092 family. 

*YAJF_ECOLI.ecard:
# Similarity:
Belongs to the ROK (nagC/xylR) family. 

*YAJR_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YBAD_ECOLI.ecard:
# Similarity:
Belongs to the UPF0168 family. 

*YBAL_ECOLI.ecard:
# Similarity:
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. 

*YBAY_ECOLI.ecard:
# Name:
Hypothetical lipoprotein ybaY precursor 

*YBCM_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ybcM 

*YBCM_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YBDL_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 

*YBES_ECOLI.ecard:
# Similarity:
Contains 1 J domain. 

*YBEV_ECOLI.ecard:
# Similarity:
Contains 1 J domain. 

*YBFI_ECOLI.ecard:
# Similarity:
Not Available

*YBGC_ECOLI.ecard:
# Similarity:
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. 

*YBGD_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YBGF_ECOLI.ecard:
# Similarity:
To P.putida hypothetical protein PP1224 precursor (ORF2) (AC P43037). 

*YBIH_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*YBJK_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*YCAO_ECOLI.ecard:
# Similarity:
Belongs to the UPF0142 family. 

*YCBQ_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YCBT_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YCBY_ECOLI.ecard:
# Similarity:
In the N-terminal section; belongs to the UPF0020 family. In the C-terminal section; belongs to the UPF0064 family. 

*YCCK_ECOLI.ecard:
# Similarity:
Belongs to the dscR/dsvC family. 

*YCDC_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*YCDY_ECOLI.ecard:
# Similarity:
Belongs to the ycdY/ynfI family. 

*YCEE_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. TCR/tet family. 

*YCEL_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YCFH_ECOLI.ecard:
# Similarity:
Belongs to the tatD DNase family. 

*YCFQ_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*YCHG_ECOLI.ecard:
# Similarity:
To insertion element IS4 hypothetical 50.4 kDa protein. Could be a "scar" from some insertion event. 

*YCIR_ECOLI.ecard:
# Similarity:
Contains 1 EAL domain. Contains 1 GGDEF domain. Contains 1 PAS (PER-ARNT-SIM) dimerization domain. 

*YCIT_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yciT 

*YCIT_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*YCJL_ECOLI.ecard:
# Similarity:
To L.lactis hypothetical protein yvdE homolog (AC P22347). 

*YCJN_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ycjnop.

*YCJO_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ycjnop. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YCJP_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ycjnop. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YCJY_ECOLI.ecard:
# Similarity:
To P.aeruginosa hypothetical protein PA2218 (AC Q01609). 

*YDAM_ECOLI.ecard:
# Similarity:
Contains 1 GGDEF domain. Contains 2 PAS (PER-ARNT-SIM) dimerization domains. Contains 1 PAS-associated C-terminal (PAC) domain. 

*YDBA_ECOLI.ecard:
# Similarity:
To S.typhimurium bigA. 

*YDCK_ECOLI.ecard:
# Similarity:
Belongs to the transferase hexapeptide repeat family. 

*YDCS_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ydcstuv.

*YDCS_ECOLI.ecard:
# Similarity:
Belongs to the bacterial extracellular solute-binding protein potD/potF family. 

*YDCU_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ydcstuv; Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YDCV_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ydcstuv; Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YDDQ_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yddopqrs. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YDDR_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yddopqrs. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YDDS_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yddopqrs.

*YDDU_ECOLI.ecard:
# Similarity:
Contains 1 EAL domain. Contains 1 GGDEF domain. Contains 2 PAS (PER-ARNT-SIM) dimerization domains. Contains 1 PAS-associated C-terminal (PAC) domain. 

*YDEJ_ECOLI.ecard:
# Similarity:
Belongs to the cinA family. 

*YDEO_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ydeO 

*YDEO_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YDEQ_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YDER_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YDES_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YDEW_ECOLI.ecard:
# Similarity:
Belongs to the sorC transcriptional regulatory family. 

*YDEY_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ego/Ydeyz. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YDEZ_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ego/Ydeyz. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YDHC_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. Bcr/cmlA family. 

*YDHD_ECOLI.ecard:
# Similarity:
Belongs to the UPF0055 family. 

*YDHF_ECOLI.ecard:
# Similarity:
Belongs to the aldo/keto reductase 2 family. 

*YDHM_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*YDHP_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YDHX_ECOLI.ecard:
# Similarity:
The iron-sulfur centers are similar to those of bacterial-type 4Fe-4S ferredoxins. 

*YDIM_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YDIN_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YDIP_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ydiP 

*YDIP_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YDJF_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ydjF 

*YDJF_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*YDJN_ECOLI.ecard:
# Similarity:
Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. 

*YEAM_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yeaM 

*YEAM_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YEBQ_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. TCR/tet family. 

*YECC_ECOLI.ecard:
# Similarity:
Belongs to the ABC transporter family. 

*YECS_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yeccs For An Amino Acid; Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YEGB_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. TCR/tet family. 

*YEGE_ECOLI.ecard:
# Similarity:
Contains 1 EAL domain. Contains 1 GGDEF domain. Contains 2 PAS (PER-ARNT-SIM) dimerization domains. Contains 3 PAS-associated C-terminal (PAC) domains. 

*YFAX_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yfaX 

*YFAX_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*YFBQ_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 

*YFCP_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YFDZ_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 

*YFEO_ECOLI.ecard:
# Similarity:
Belongs to the chloride channel (TC 1.A.11) family. 

*YFGB_ECOLI.ecard:
# Similarity:
Belongs to the UPF0063 family. 

*YFHC_ECOLI.ecard:
# Similarity:
Belongs to the cytidine and deoxycytidylate deaminase family. 

*YFHF_ECOLI.ecard:
# Similarity:
Belongs to the hesB/yadR/yfhF family. 

*YFHK_ECOLI.ecard:
# Specific_Function:
Probable Member Of A Two-Component Regulatory System Yfha/Yfhk. May Activate Yfha By Phosphorylation.

*YFHP_ECOLI.ecard:
# Similarity:
Belongs to the UPF0074 (rff2) family. 

*YFIN_ECOLI.ecard:
# Similarity:
Belongs to the yaiC / yfiN (E.coli), yhcK (B.subtilis) family. Contains 1 GGDEF domain. Contains 1 HAMP domain. 

*YFJR_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yfjR 

*YFJR_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*YGAD_ECOLI.ecard:
# Similarity:
Belongs to the cinA family. 

*YGAP_ECOLI.ecard:
# Similarity:
Contains 1 rhodanese domain. Strong, to Synechocystis PCC 6803 slr1261. 

*YGAV_ECOLI.ecard:
# Similarity:
Contains 1 HTH arsR-type DNA-binding domain. 

*YGAY_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YGBI_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ygbI 

*YGBI_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*YGDQ_ECOLI.ecard:
# Similarity:
Belongs to the UPF0053 family. 

*YGEK_ECOLI.ecard:
# Name:
Hypothetical response regulatory protein ygeK 

*YGEK_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. Contains 1 response regulatory domain. 

*YGGG_ECOLI.ecard:
# Specific_Function:
Seems To Regulate The Expression Of Speb.

*YGIL_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YGJU_ECOLI.ecard:
# Similarity:
Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. 

*YHBE_ECOLI.ecard:
# Similarity:
Belongs to the eamA transporter family. 

*YHBX_ECOLI.ecard:
# Specific_Function:
Involved In Adherence (By Similarity).

*YHDW_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ydhwxyz For An Amino Acid.

*YHDW_ECOLI.ecard:
# Similarity:
Belongs to the bacterial extracellular solute-binding protein family 3. 

*YHDX_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ydhwxyz For An Amino Acid; Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YHDY_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ydhwxyz For An Amino Acid; Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YHGN_ECOLI.ecard:
# Similarity:
Belongs to the UPF0056 (marC) family. 

*YHHT_ECOLI.ecard:
# Similarity:
Belongs to the UPF0118 (perM) family. 

*YHIF_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. 

*YHIW_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yhiW 

*YHIW_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YHJB_ECOLI.ecard:
# Similarity:
Contains 1 HTH luxR-type DNA-binding domain. 

*YHJK_ECOLI.ecard:
# Similarity:
Contains 1 EAL domain. Contains 1 GGDEF domain. Contains 1 HAMP domain. 

*YIAD_ECOLI.ecard:
# Similarity:
Belongs to the ompA family. 

*YIAJ_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yiaJ 

*YIAJ_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*YIAN_ECOLI.ecard:
# Similarity:
Belongs to the yiaN/ygiK family. 

*YIAO_ECOLI.ecard:
# Similarity:
Belongs to the bacterial extracellular solute-binding protein family 7. 

*YICG_ECOLI.ecard:
# Similarity:
Belongs to the UPF0126 family. 

*YIDL_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yidL 

*YIDL_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YIDY_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YIEO_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. EmrB family. 

*YIGZ_ECOLI.ecard:
# Similarity:
Belongs to the UPF0029 family. 

*YIHW_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yihW 

*YIHW_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*YIJC_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*YIJO_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yijO 

*YIJO_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YJFJ_ECOLI.ecard:
# Similarity:
Belongs to the pspA/IM30 family. 

*YJFQ_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yjfQ 

*YJFQ_ECOLI.ecard:
# Similarity:
Contains 1 HTH deoR-type DNA-binding domain. 

*YJGF_ECOLI.ecard:
# Similarity:
Belongs to the UPF0076 (UK114) family. 

*YJGJ_ECOLI.ecard:
# Similarity:
Contains 1 HTH tetR-type DNA-binding domain. 

*YJHI_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yjhI 

*YJHI_ECOLI.ecard:
# Similarity:
Contains 1 HTH iclR-type DNA-binding domain. 

*YJHQ_ECOLI.ecard:
# Similarity:
Belongs to the acetyltransferase family. 

*YJHT_ECOLI.ecard:
# Similarity:
Contains 7 Kelch repeats. 

*YJHU_ECOLI.ecard:
# Similarity:
Belongs to the sorC transcriptional regulatory family. 

*YJIL_ECOLI.ecard:
# Similarity:
Not Available

*YJIO_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YJJV_ECOLI.ecard:
# Similarity:
Belongs to the tatD DNase family. 

*YKFC_ECOLI.ecard:
# Similarity:
To mitochondrial and chloroplast and group II intron maturases. 

*YKGA_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ykgA 

*YKGA_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YKGC_ECOLI.ecard:
# Similarity:
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. 

*YKGD_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ykgD 

*YKGD_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YLEA_ECOLI.ecard:
# Similarity:
Belongs to the UPF0004 family. Contains 1 TRAM domain. 

*YLIB_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yliabcd.

*YLIC_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yliabcd; Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YLID_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yliabcd; Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YMFK_ECOLI.ecard:
# Similarity:
Not Available

*YNFA_ECOLI.ecard:
# Name:
Hypothetical UPF0060 protein ynfA 

*YNFI_ECOLI.ecard:
# Similarity:
Belongs to the ycdY/ynfI family. 

*YNFM_ECOLI.ecard:
# Similarity:
Belongs to the major facilitator superfamily. 

*YNJC_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Ynjcd. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YOJI_ECOLI.ecard:
# Similarity:
Belongs to the ABC transporter family. 

*YPDC_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator ypdC 

*YPDC_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YPHD_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yphdef. Probably Responsible For The Translocation Of The Substrate Across The Membrane.

*YPHF_ECOLI.ecard:
# Specific_Function:
Probably Part Of The Binding-Protein-Dependent Transport System Yphdef.

*YQAB_ECOLI.ecard:
# Similarity:
Belongs to the cbbY/cbbZ/gph/yieH family. 

*YQHC_ECOLI.ecard:
# Name:
Putative HTH-type transcriptional regulator yqhC 

*YQHC_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*YQII_ECOLI.ecard:
# Name:
Hypothetical protein yqiI precursor 

*YRAH_ECOLI.ecard:
# Similarity:
Belongs to the fimbrial protein famly. 

*YRBA_ECOLI.ecard:
# Similarity:
Belongs to the bolA / yrbA family. 

*YRBF_ECOLI.ecard:
# Similarity:
Belongs to the ABC transporter family. 

*YTFL_ECOLI.ecard:
# Similarity:
Belongs to the UPF0053 family. Contains 2 CBS domains. 

*CHBR_ECOLI.ecard:
# Name:
HTH-type transcriptional regulator chbR 

*CHBR_ECOLI.ecard:
# Alternate_Names:
Chb operon repressor

*CHBR_ECOLI.ecard:
# Similarity:
Contains 1 HTH araC/xylS-type DNA-binding domain. 

*CLCA_ECOLI.ecard:
# Similarity:
Belongs to the chloride channel (TC 1.A.11) family. 

*CLCB_ECOLI.ecard:
# Similarity:
Belongs to the chloride channel (TC 1.A.11) family. 

*NSR_ECOLI.ecard:
# Similarity:
Contains 1 cyclic nucleotide-binding domain. Contains 1 HTH crp/fnr-type DNA-binding domain.